Omics Atlas
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Longitudinal serum proteome mapping for healthy ageing and related cardiometabolic diseases



Tang et al., Under Review, 2024

The Laboratory of Precision Nutrition and Computational Medicine

Westlake University

Eighty-six Proteins Associated with Aging

Through a longitudinal analysis of three time points in a 9-year follow-up study of 3796 middle-aged and elderly individuals, we identified 86 proteins that are related to age. The association patterns of these proteins with age were consistent in both the discovery and validation sets.

Search for the Association Analysis Results in the Table

Association of 86 Age-Related Proteins with Healthy Aging

We further conducted statistical regression analysis, correlating these 86 proteins with 32 clinical features and the incidence rates of 14 major age-related chronic diseases. These proteins exhibit a high correlation with healthy aging and related cardiometabolic diseases.

Explore the Association of 86 Proteins with Chronic Diseases Search for the Association Analysis Results in the Table